Role of Dynamic Susceptibility Contrast Perfusion MRI in Glioma Progression Evaluation

Dynamic susceptibility contrast perfusion MRI (with pitfalls)

Since the first studies in the late 1980s and early 1990s, dynamic susceptibility contrast MRI (DSC-MRI, also known as ‘bolus tracking’) has become a very powerful technique for the assessment of perfusion, and perfusion-related parameters (see (1,2) for recent reviews). Despite the need of an exogenous MR agent (cf. arterial spin labeling techniques), DSC-MRI is currently the most common MR pe...

Diffusion tensor and dynamic susceptibility contrast- enhanced perfusion MRI for the assessment of glioma proliferation

Dynamic susceptibility contrast MRI

Introduction Quantitative dynamic susceptibility contrast perfusion MRI (DSC-MRI) is based on the monitoring of the first passage of a bolus of contrast agent through the brain tissue and a brain-feeding artery. The contrast agent is injected rapidly by means of an MRinjector in the antecubital vein in the patients arm and a saline flush is used to push the contrast agent into the direction of ...

Evaluation of Encephaloduroarteriosynangiosis Efficacy Using Probabilistic Independent Component Analysis Applied to Dynamic Susceptibility Contrast Perfusion MRI.

BACKGROUND AND PURPOSE Indirect cerebral revascularization has been successfully used for treatment in Moyamoya disease and symptomatic intracranial atherosclerosis. While angiographic neovascularization has been demonstrated after surgery, measurements of local tissue perfusion are scarce and may not reflect the reported successful clinical outcomes. We investigated probabilistic independent c...

Dynamic Susceptibility Contrast-MRI Quantification Software Tool: Development and Evaluation

Relative cerebral blood volume (rCBV) is a magnetic resonance imaging biomarker that is used to differentiate progression from pseudoprogression in patients with glioblastoma multiforme, the most common primary brain tumor. However, calculated rCBV depends considerably on the software used. Automating all steps required for rCBV calculation is important, as user interaction can lead to increase...